{"id":67,"date":"2026-03-08T17:55:54","date_gmt":"2026-03-08T16:55:54","guid":{"rendered":"https:\/\/epilogy.org\/?p=67"},"modified":"2026-03-22T19:59:50","modified_gmt":"2026-03-22T18:59:50","slug":"nma-studio","status":"publish","type":"post","link":"https:\/\/epilogy.org\/fr\/nma-studio","title":{"rendered":"NMA Studio"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"67\" class=\"elementor elementor-67\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c71db69 e-flex e-con-boxed e-con e-parent\" data-id=\"c71db69\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-31180f0 elementor-widget elementor-widget-heading\" data-id=\"31180f0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">A web application to produce and visualise interactive outputs from network meta-analyses<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bce8cd8 elementor-widget elementor-widget-html\" data-id=\"bce8cd8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<style>\n\n.epilogy-review{\n  background:#fff;\n  border:1px solid #ead3ee;\n  border-left:5px solid #7C2A86;\n  border-radius:8px;\n  padding:20px;\n  margin:24px 0;\n}\n\n.epilogy-review h2,\n.epilogy-review h3{\n  font-size:14px;\n  color:#7C2A86;\n  margin:0 0 10px 0;\n  line-height:1.4;\n}\n\n.epilogy-review p{\n  font-size:13px;\n  color:#54595F;\n  line-height:1.7;\n  margin:0 0 12px 0;\n}\n\n.epilogy-review ul{\n  margin:0 0 12px 18px;\n  padding:0;\n}\n\n.epilogy-review li{\n  font-size:13px;\n  color:#54595F;\n  line-height:1.7;\n  margin:0 0 8px 0;\n}\n\n.epilogy-review strong{\n  color:#7C2A86;\n  font-weight:600;\n}\n\n\/* ACCORDION *\/\n\n.epilogy-accordion details{\n  padding-top:10px;\n  margin-top:10px;\n  border-top:1px solid #f0e4f3;\n}\n\n.epilogy-accordion summary{\n  font-size:14px;\n  color:#7C2A86;\n  cursor:pointer;\n  font-weight:600;\n  list-style:none;\n}\n\n.epilogy-accordion summary::-webkit-details-marker{\n  display:none;\n}\n\n.epilogy-accordion summary::after{\n  content:\"+\";\n  float:right;\n}\n\n.epilogy-accordion details[open] summary::after{\n  content:\"\u2013\";\n}\n\n.epilogy-accordion p,\n.epilogy-accordion ul{\n  margin-top:10px;\n}\n\n\/* Figure *\/\n\n.epilogy-figure{\n  margin:14px 0;\n  text-align:center;\n}\n\n.epilogy-figure img{\n  max-width:80%;\n  height:auto;\n  border-radius:6px;\n}\n\n.epilogy-caption{\n  font-size:12px;\n  color:#8a8a8a;\n  text-align:center;\n  margin-top:6px;\n}\n\n\/* Researchers *\/\n\n.epilogy-person{\n  display:flex;\n  gap:12px;\n  align-items:flex-start;\n  margin:14px 0;\n}\n\n.epilogy-person img{\n  width:60px;\n  height:60px;\n  border-radius:50%;\n  border:2px solid #7C2A86;\n  object-fit:cover;\n}\n\n.epilogy-person-name{\n  font-weight:600;\n  color:#7C2A86;\n  margin-bottom:4px;\n}\n\n@media (max-width:767px){\n  .epilogy-review{\n    padding:16px;\n  }\n}\n\n<\/style>\n\n<div class=\"epilogy-review epilogy-accordion\">\n\n<h2>Network meta-analysis and multiplicity of results<\/h2>\n\n<p>Network Meta-Analysis (NMA) combines data from different studies on multiple treatments in order to estimate their relative effects.<\/p>\n\n<p>The amount of evidence to analyse and interpret can be demanding, especially when numerous treatments are involved.<\/p>\n\n<p>Software available so far did not provide satisfactory solutions to improve the visualisation and sorting of large and\/or complex results.<\/p>\n\n\n<details>\n<summary>NMA studio: a new interactive tool<\/summary>\n\n<p>It is in this context that NMA studio was developed in 2020, to produce and visualise network meta-analyses in a fully interactive way. As a web application, NMA studio improves visualisation while simplifying the reporting and interpretation of results.<\/p>\n\n<p>The main feature of the tool is a direct visual connection between a customisable network diagram and the main results of the network meta-analysis.<\/p>\n\n<p>Users can upload their data and interact with the network diagram by clicking on:<\/p>\n\n<ul>\n<li>One or several nodes (treatments).<\/li>\n<li>Or edges (comparisons).<\/li>\n<\/ul>\n\n<p>Depending on the selection, customised results and information are displayed.<\/p>\n\n<div class=\"epilogy-figure\">\n<img decoding=\"async\" src=\"https:\/\/epilogy.org\/wp-content\/uploads\/2026\/03\/plot-nma-studio.png\" style=\"max-width:50%;\">\n<\/div>\n\n<\/details>\n\n\n<details>\n<summary>NMA studio: a free open-source application<\/summary>\n\n<p>NMA studio uses the Python programming language while being connected to the \n<a href=\"https:\/\/cran.r-project.org\/web\/packages\/netmeta\/index.html\" target=\"_blank\">\nR netmeta package (Network Meta-Analysis using Frequentist Methods)\n<\/a>\nto generate analyses.<\/p>\n\n<p>The results are then imported into Python where interactive and downloadable visualisations are created using \u201cPlotly\u201d modules.<\/p>\n\n<p>No prior knowledge of these tools is required to use NMA studio. The application is open source and can be accessed free of charge via any web browser at:\n<a href=\"https:\/\/nmastudio.uiocloud.no\/\" target=\"_blank\">www.nmastudioapp.com<\/a><\/p>\n\n<\/details>\n\n\n<details>\n<summary>\n<a href=\"https:\/\/cinema.med.auth.gr\/\" target=\"_blank\">\nCINeMA (Confidence in Network Meta-Analysis)\n<\/a>\n<\/summary>\n\n<p>NMA studio allows users to upload the CINeMA (Confidence in Network Meta-Analysis)report file in its original format to provide additional visualisations. <a href=\"https:\/\/cinema.ispm.unibe.ch\/\" target=\"_blank\">CINeMA<\/a> is a web application that simplifies the assessment of confidence in the results of a network meta-analysis.<\/p>\n\n<div class=\"epilogy-figure\">\n<img decoding=\"async\" src=\"https:\/\/epilogy.org\/wp-content\/uploads\/2026\/03\/figures_NMA_Studio.png\">\n<div class=\"epilogy-caption\">\nNetwork plot of serious adverse events and PASI 90 for systemic psoriasis treatments. Node size is proportional to the total number of participants, and line thickness is proportional to the number of studies.\n<\/div>\n<\/div>\n\n<div class=\"epilogy-figure\">\n<a href=\"https:\/\/cinema.ispm.unibe.ch\/\" target=\"_blank\">\n<img decoding=\"async\" src=\"https:\/\/epilogy.org\/wp-content\/uploads\/2026\/03\/CINeMA.svg\" style=\"max-width:160px;\">\n<\/a>\n<\/div>\n\n<\/details>\n\n\n<details>\n<summary>Two researchers behind the NMA studio project<\/summary>\n\n<div class=\"epilogy-person\">\n<img decoding=\"async\" src=\"https:\/\/epilogy.org\/wp-content\/uploads\/2026\/03\/sylvia-metelli.png\">\n<div>\n<div class=\"epilogy-person-name\">Silvia Metelli<\/div>\n<p>Universit\u00e9 de Paris, Research Center of Epidemiology<br>\nand Statistics (CRESS-U1153), Inserm,<br>\nParis, France<\/p>\n<\/div>\n<\/div>\n\n<div class=\"epilogy-person\">\n<img decoding=\"async\" src=\"https:\/\/epilogy.org\/wp-content\/uploads\/2026\/03\/Anna-Chaimani.png\">\n<div>\n<div class=\"epilogy-person-name\">Anna Chaimani<\/div>\n<p>Universit\u00e9 de Paris, Research Center of Epidemiology<br>\nand Statistics (CRESS-U1153), Inserm, Paris, France<br>\nCochrane France, Paris, France<\/p>\n<\/div>\n<\/div>\n\n<p>Page created using \n<a href=\"https:\/\/epilogy.org\/wp-content\/uploads\/2026\/03\/NMAstudio_tutorial.pdf\" target=\"_blank\">\nNMA studio web-application: A brief tutorial\n<\/a>\nby Silvia Metelli and Anna Chaimani.<\/p>\n\n<\/details>\n\n<\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-be0a3e1 e-flex e-con-boxed e-con e-parent\" data-id=\"be0a3e1\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5798ffd elementor-widget elementor-widget-heading\" data-id=\"5798ffd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">A systematic review as a demonstration<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9e185ee elementor-widget elementor-widget-html\" data-id=\"9e185ee\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<style>\n.epilogy-highlight{\n  background:#FADFFF;\n  border-radius:6px;\n  padding:14px 16px;\n  margin:0 0 16px 0;\n}\n\n.epilogy-highlight p{\n  font-size:13px;\n  color:#54595F;\n  line-height:1.7;\n  margin:0 0 12px 0;\n}\n\n.epilogy-highlight ul{\n  margin:0 0 12px 18px;\n  padding:0;\n}\n\n.epilogy-highlight li{\n  font-size:13px;\n  color:#54595F;\n  line-height:1.7;\n  margin:0 0 8px 0;\n}\n\n.epilogy-highlight a{\n  color:#7C2A86;\n  text-decoration:none;\n  font-weight:600;\n}\n\n.epilogy-highlight a:hover{\n  text-decoration:underline;\n}\n\n.epilogy-highlight .no-bold{\n  font-weight:400;\n}\n<\/style>\n\n<div class=\"epilogy-highlight\">\n\n<p>To demonstrate the tool, a network of 158 Randomised Controlled Trials (RCTs) comparing 20 treatments for plaque psoriasis evaluated within a Cochrane systematic review* was used.<\/p>\n\n<p>Two outcomes were analysed, one measuring treatment efficacy and one measuring safety:<\/p>\n\n<ul>\n<li>Efficacy: proportion of participants achieving a Psoriasis Area Severity Index \u2265 90 (PASI 90).<\/li>\n<li>Safety: Serious Adverse Events (SAEs).<\/li>\n<\/ul>\n\n<p>This dataset is permanently loaded as the default project so that users can familiarise themselves with NMA studio before uploading their own data.<\/p>\n\n<p><em>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35603936\/\" target=\"_blank\">\nSystemic pharmacological treatments for chronic plaque psoriasis: a network meta-analysis\n<\/a><br>\nSbidian E, Chaimani A, Garcia-Doval I, Doney L, Dressler C, Hua C, Hughes C, Naldi L, Afach S, Le Cleach L.<br>\nCochrane Database Syst Rev. 2022 May 23;5(5):CD011535.<br>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35603936\/\" class=\"no-bold\" target=\"_blank\">\ndoi: 10.1002\/14651858.CD011535.pub5.\n<\/a> PMID: 35603936 Review.\n<\/em><\/p>\n\n<\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c4ddd9e e-flex e-con-boxed e-con e-parent\" data-id=\"c4ddd9e\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-88deaa9 elementor-widget elementor-widget-html\" data-id=\"88deaa9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<script>\ndocument.querySelectorAll('.epilogy-accordion details').forEach((detail) => {\n  detail.addEventListener('toggle', function() {\n    if (this.open) {\n      document.querySelectorAll('.epilogy-accordion details').forEach((other) => {\n        if (other !== this) {\n          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The amount of evidence to analyse and interpret can be demanding, especially when numerous treatments are involved. Software available&hellip;&nbsp;<a href=\"https:\/\/epilogy.org\/fr\/nma-studio\" rel=\"bookmark\"><span class=\"screen-reader-text\">NMA Studio<\/span><\/a><\/p>","protected":false},"author":1,"featured_media":525,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"off","neve_meta_content_width":70,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","neve_meta_reading_time":"","footnotes":""},"categories":[8],"tags":[],"class_list":["post-67","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cochrane"],"_links":{"self":[{"href":"https:\/\/epilogy.org\/fr\/wp-json\/wp\/v2\/posts\/67","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/epilogy.org\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/epilogy.org\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/epilogy.org\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/epilogy.org\/fr\/wp-json\/wp\/v2\/comments?post=67"}],"version-history":[{"count":43,"href":"https:\/\/epilogy.org\/fr\/wp-json\/wp\/v2\/posts\/67\/revisions"}],"predecessor-version":[{"id":586,"href":"https:\/\/epilogy.org\/fr\/wp-json\/wp\/v2\/posts\/67\/revisions\/586"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/epilogy.org\/fr\/wp-json\/wp\/v2\/media\/525"}],"wp:attachment":[{"href":"https:\/\/epilogy.org\/fr\/wp-json\/wp\/v2\/media?parent=67"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/epilogy.org\/fr\/wp-json\/wp\/v2\/categories?post=67"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/epilogy.org\/fr\/wp-json\/wp\/v2\/tags?post=67"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}